Skip to main content
Figure 2 | Reproductive Biology and Endocrinology

Figure 2

From: MicroRNA-181a is involved in the regulation of human endometrial stromal cell decidualization by inhibiting Krüppel-like factor 12

Figure 2

miR-181a inhibition attenuates hESC decidualization in vitro . hESC were transfected with a miR-181a inhibitor or a miRNA inhibitor negative control (miRNA inhibitor control, 100 nM) for 24 h, and then cells were treated with or without 0.5 mM 8-Br-cAMP and 1 μM MPA (8Br + MPA) for an additional 72 h. miR-181 family (A), FOXO1A (B), PRL (C), IGFBP1 (D), DCN (E), and TIMP3 (F) mRNA expression levels were examined by qRT-PCR. *p < 0.05, bars labeled with different letters indicate statistically significant differences (p < 0.05). (G) The decidual transformation change of hESC based on the distribution of the actin filaments.

Back to article page

Reproductive Biology and Endocrinology

ISSN: 1477-7827

Contact us