Figure 3

- Murine blood vessels in sheep ovarian transplants after 3 days and 3 weeks reflect colonisation by host vessels into the graft. A. An illustration of murine blood vessels that were stained with a mouse-specific CD31 Ab in an ovarian fragment that was treated with VEGF₁₆₅ and removed 3 days after transplantation. The host tissue is identified by the dotted arrow, and the graft is identified by the plain arrow. B. The quantification of murine blood vessels in the grafted tissue 3 days after transplantation. In the treated mice, 6 of 15 fragments contained CD31-positive blood vessels compared with only 3 of 14 fragments in the control mice. C. The quantification of murine blood vessels in the grafted tissue 3 weeks after transplantation. All of the fragments in both the control and treated groups contained CD31-positive blood vessels. n corresponds to the number of transplanted ovarian fragments that contained murine blood vessels. Scale bar: 200 μm. **Corresponds to a p value < 0.01. Error bar are SEM.