Pregnancy outcomes in women with repeated implantation failures after intracytoplasmic morphologically selected sperm injection (IMSI)

Table 2 Subpopulations with or without male factor; comparison between morphologically selected sperm injection (IMSI) and conventional intracytoplasmic sperm injection (ICSI) study groups.

	With male factor			Without male factor
	IMSI	ICSI	P	IMSI	ICSI	P
Cycles (n)	37	45		63	55
Female age (years)	36.9 ± 4.0	35.6 ± 3.9	0.11	36.6 ± 4.0	37.7 ± 3.9	0.13
Male age (years)	40.6 ± 6.4	41.9 ± 6.5	0.34	39.3 ± 6.0	39.0 ± 5.3	0.79
Number of failures	3.1 ± 1.6	3.4 ± 1.9	0.64	3.4 ± 1.7	3.0 ± 1.3	0.20
Aetiology (%)
Male	78.4	77.8	0.08			0.33
Idiopathic	0	0		38	30.9
Tuboperitoneal	0	0		30.2	25.4
Endometriosis	0	0		28.6	32.7
Male + endometriosis	16.2	4.4		0	0
Tuboperitoenal+ endometriosis	0	0		3.2	11
Male+tuboperitoneal	5.4	17.8		0	0
MSOME ^a
Normal spermatozoa (%)	0.3 ± 0.3	0.3 ± 0.3	0.79	2.4 ± 1.9	2.5 ± 2.1	> 0.99
Semen Parameters
Total sperm count (x10⁶/mL)	14.2 ± 18.4	11.8 ± 14.9	0.86	95.8 ± 88.9	98.9 ± 52.5	0.82
Motility (% spermatozoa)	35.5 ± 14.1	29.6 ± 15.6	0.12	60.9 ± 16.2	61.1 ± 10.8	0.94
(rapid+slowprogression)	49.6 ± 15.8	47.2 ± 15.2	0.54	65.5 ± 15.9	70 ± 6.3	0.56
Vitality (%) (mean ± SD)	0.3 ± 0.3	0.4 ± 0.5	0.21	0.4 ± 0.8	0.5 ± 0.3	0.16
Leukocytes in semen (x10⁶) (mean ± SD)
Number of oocytes
Mature (MII)	8.0 ± 5.1	7.8 ± 3.7	0.82	6.6 ± 4.4	5.9 ± 3.1	0.56
Total	10.7 ± 6.8	9.4 ± 4.6	0.61	8.7 ± 5.7	7.6 ± 4.4	0.44
Fertilisation rate (%)	59.1 ± 23.1	57.8 ± 25.2	0.61	68.1 ± 24.4	65.4 ± 27.4	0.72
Embryos transfer (n)	2.6 ± 1.0	2.8 ± 1.1	0.69	2.7 ± 1.1	2.6 ± 1.0	0.63
High-quality embryo transfer (n)	1.5 ± 0.5	1.5 ± 0.5	0.89	1.4 ± 0.5	1.5 ± 0.5	0.55
Implantation rate (%)	11.8	11.2	0.88	14.6	8.6	0.16
Pregnancy/cycle (%)	32.4	24.4	0.57	22.2	14.5	0.40
Miscarriage (%)	16.7	36.4	0.54	14.3	25	0.95
Ongoing pregnancy/cycle (%)	27	15.5	0.31	19	10.9	0.33
Live birth/cycle (%)	27	15.5	0.31	17.5	9.1	0.29

ISSN: 1477-7827