Table 1 Successful use of anastrozole in the treatment of endometriosis associated symptoms
From: The emerging use of aromatase inhibitors for endometriosis treatment
Patient group | Summary of Results | Reference |
|---|---|---|
Case report (one post-menopausal patient, recurrent endometriosis) | Rapid decrease in pelvic pain Decrease in implant mass | [18] Takayama et al. |
Pre-menopausal women (N = 2) (intolerant/failed previous treatment, severe pain symptoms) | Decrease in associated symptoms Decrease in implant mass (1 of 2 patients) | [19] Shippen & West |
Pre-menopausal women (N = 15) (refractory endometriosis, pelvic pain) | Decreased pelvic pain, affect on implant mass not determined | [20] Amsterdam et al. |
Pre-menopausal women (N = 80) (prior conservative surgical therapy; N = 40 goserelin vs. N = 40 goserelin + anastrozole) | Decreased symptom recurrence rate Increased pain-free interval | [21] Soysal et al. |
Pre-menopausal women (N = 10) (endometriosis resistant to conventional therapy) | Increased quality of life, decreased dyspareunia (9/10 patients), change in implant mass inconclusive | [22] Hefler et al. |
Pre-menopausal women (N = 3) (endometriosis resistant to conventional therapy) | Decreased pelvic pain, affect on implant mass not determined | [23] Verma & Konje |