Reference | Mean GA | Outcome | Cases (Preeclampsia) | Controls (normotensive) | P-value | % difference†| ||
---|---|---|---|---|---|---|---|---|
 |  |  | n | Flt-1 concentration | n | sFlt-1 concentration |  |  |
Studies reporting mean concentrations | mean, SD/SE | Â | mean, SD/SE | Â | Â | |||
Baumann, 2008 | 12.3 | PE (> 34 weeks) | 46 | 1764 (757) | 92 | 1537 (812) | 0.04 | +13 |
Chaiworapongsa, 2005 | 12.3 | PE | 34 | 546 (271) | 37 | 464 (260) | 0.10 | +15 |
Lynch, 2010 | 12.3 | PE | 31 | 1374 (639) | 637 | 1313 (521) | 0.5 | +5 |
Noori, 2010 | 13.7 | PE (< 37 weeks) | 10 | 2414 (622) | 128 | 1729 (85) | < 0.01 | +40 |
 |  | PE (≥ 37 weeks) | 10 | 1688 (210) | 128 | 1729 (85) | 0.19 | - 2 |
Rana S, 2007 | 11-13* | PE | 39 | 3500 (300) | 147 | 3000 (100) | 0.14 | +14 |
Thadhani, 2004 | 10.7 | PE | 40 | 1048 (657) | 80 | 973 (490) | > 0.05 | + 7 |
Vatten, 2007 | 9.0 | Preterm PE | 110 | 135 | 276 | 166 | 0.01 | -19 |
Studies reporting median concentrations | median | Â | median | Â | Â | |||
Akolekar 2010 | 11-13* | PE (< 34 weeks) | 30 | 7099 | 180 | 6349 | NS | +12 |
 |  | PE (≥ 34 weeks) | 60 | 6840 | 180 | 6349 | NS | + 8 |
Erez, 2008 | 12.2 | PE (< 37 weeks) | 17 | 1308 | 201 | 1788 | 0.03 | -27 |
 | 12.2 | PE (≥ 37 weeks) | 39 | 1448 | 201 | 1788 | 0.02 | -19 |
Wathen, 2006 | 13.7 | PE | 44 | 481 | 51 | 432 | > 0.05 | +10 |