Equol an isoflavonoid: potential for improved prostate health, in vitro and in vivoevidence

Table 2 Serum 5α-DHT levels, prostate weights and reproductive parameters in Equol-treated male rats

Parameter measured	Vehicle	Equol	Change
Prostate Weight (PW), mg	535 ± 23	429 ± 30**	20%↓
PW/100 g Body Weight	76 ± 4	61 ± 5**	20%↓
Luteinizing Hormone (LH), ng/ml	1.6 ± 0.2	1.3 ± 0.1	NSC
Serum Testosterone, ng/ml	2.1 ± 0.4	2.3 ± 0.5	NSC
Serum 5α-DHT, pg/ml	100 ± 18	52 ± 5*	50%↓
Serum 17β-Estradiol, pg/ml	3.4 ± 0.6	4.8 ± 0.7	NSC

n = 8 animals per group. NSC = no significant change. The data are expressed as the mean ± standard error of the mean (sem) for each parameter.
** = p < 0.016 * = p < 0.001

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