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Table 1 Characteristics of various phenotypes of androgen excess and/or anovulation

From: The prevalence of idiopathic hirsutism and polycystic ovary syndrome in the Tehran Lipid and Glucose Study

Group

Group1

(PCOS)

N = 85

Group 2

menstrual dysfunction per se

N = 15

Group 3

(CH+BH)

N = 43

Group 4

(IH)

N = 130

Group 5

(Normal)

N = 718

Age

a 27.0 (21.0-35.0)

29.0 (20.0-34.5)

30.0 (23.0-35.0)

33.0 (26.0-38.0)

29.0 (21.0-36.0)

Age at menarche

13.0 (12.0-13.0)

13.0 (12.5-13.5)

13.0 (13.0-14.0)

13.0 (12.0-14.0)

13.0 (13.0-14.0)

Women with history of primary Infertility %

b 8.2

5.7

3.7

2.2

1.7

Women with family history of hirsutism %

b 58.8

39.6

b 40.7

b 49.6

24.9

Women with family history of anovulation %

b 32.9

30.2

29.6

24.1

17.0

Women with family history of infertility %

b 9.4

3.8

4.8

2.9

2.9

Women with history of abortion %

14.1

18.9

11.1

17.5

17.3

No. Pregnancy

1.0 (0-2.0)

1 (0-2.0)

0 (0-2)

2.0 (1.0-3.0)

1 (0-2)

BMI (kg/m2)

26.2 (22.3-30.5)

26.2 (22.4-29.2)

24.1 (22.1-27.9)

b 26.7 (23.7-29.7)

24.5 (21.2-28.7)

Waist circumference (cm)

85.0 (78.0-98.5)

83.0 (75.5-92.5)

81.0 (74.0-92.0)

88.0 (79.5-98.5)

82.0 (73.0-91.0)

Hip circumference (cm)

104.0 (97.0-110.5)

101.0 (96-109.5)

99.0 (94.0-110.0)

b 105.0 (100.0-110.5)

101.0 (95.0-107.8)

Wrist circumference (cm)

15.5 (15.0-16.5)

15.5 (15.0-16.2)

15.2 (14.5-16.0)

15.8 (15.2-16.5)

15.5 (15.0-16.2)

Systolic Blood Pressure (mmHg)

102.5 (98.0-111.3)

100.0 (90.3-112.3)

106.0 (98.0-112.3)

106.5 (98.3-116.8)

106.0 (98.0-114.0)

Diastolic Blood Pressure (mmHg)

70.0 (65.0-75.0)

70.0 (68.8-81.3)

72.0 (68.8-81.3)

71.5 (65.0-77.0)

71.0 (64.0-76.0)

FBS

87.0 (81.5-91.5)

101.0 (96.0-109.5)

86.0 (81.0-89.0)

87.0 (81.3-95.0)

86.0 (81.0-92.0)

TT

a 0.5 (0.3-0.7)

0.5 (0.4-0.8)

c 0.4 (0.3-0.8)

d 0.3 (0.2-0.4)

0.4 (0.2-0.6)

SHBG

b, e 37.0 (27.0-43.0)

b, f 58.0 (46.0-106.0)

36.0 (25.0-41.0)

b, d 38.0 (28.0-45.0)

45.5 (39.0-54.8)

FAI

a, b, e 3.4 (2.2-3.8)

f 2.1 (2.0-4.4)

c 5.1 (3.2-7.7)

2.4 (1.9-3.6)

2.4 (1.5-4.2)

DHEAS

119.0 (77.0-162.3)

122.0 (85.7-139.2)

c 180.0 (123.0-221.8)

96.0 (64.0-130.0)

124.0 (75.5-145.3)

A4

b 1.4 (0.6-2.3)

1.1 (0.3-1.4)

1.5 (0.9-2.7)

1.1 (0.5-1.6)

0.8 (0.5-1.7)

  1. PCOS, polycystic ovary syndrome using NIH definition; CH, clinical hyperandrogenism; BH, biochemical hyperandrogenemia; IH, idiopathic hirsutism; Normal group, eumenorrheic without hirsutism. BMI, body mass index; DHEAS, Dehydroepiandrosterone sulfate; Total T, Total testosterone; A4, Androstendion; SHBG, Sex Hormone Binding Globulin; FAI, Free androgen index
  2. Values are given as median (Inter quartile range), a = Group 1 vs. Group 4; b = vs. normal group, p < 0.001, c = Group 3 vs. Group 4, p < 0.001; d = Group 2 vs. Group 4, p < 0.001; e = Group1 vs. Group 2, p < 0.001; f = Group 2 vs. Group 3, p < 0.001
  3. The hormonal profile of women on hormonal therapy (n = 31) were excluded from statistical analysis.
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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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