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Table 1 Characteristics of various phenotypes of androgen excess and/or anovulation

From: The prevalence of idiopathic hirsutism and polycystic ovary syndrome in the Tehran Lipid and Glucose Study

Group Group1
(PCOS)
N = 85
Group 2
menstrual dysfunction per se
N = 15
Group 3
(CH+BH)
N = 43
Group 4
(IH)
N = 130
Group 5
(Normal)
N = 718
Age a 27.0 (21.0-35.0) 29.0 (20.0-34.5) 30.0 (23.0-35.0) 33.0 (26.0-38.0) 29.0 (21.0-36.0)
Age at menarche 13.0 (12.0-13.0) 13.0 (12.5-13.5) 13.0 (13.0-14.0) 13.0 (12.0-14.0) 13.0 (13.0-14.0)
Women with history of primary Infertility % b 8.2 5.7 3.7 2.2 1.7
Women with family history of hirsutism % b 58.8 39.6 b 40.7 b 49.6 24.9
Women with family history of anovulation % b 32.9 30.2 29.6 24.1 17.0
Women with family history of infertility % b 9.4 3.8 4.8 2.9 2.9
Women with history of abortion % 14.1 18.9 11.1 17.5 17.3
No. Pregnancy 1.0 (0-2.0) 1 (0-2.0) 0 (0-2) 2.0 (1.0-3.0) 1 (0-2)
BMI (kg/m2) 26.2 (22.3-30.5) 26.2 (22.4-29.2) 24.1 (22.1-27.9) b 26.7 (23.7-29.7) 24.5 (21.2-28.7)
Waist circumference (cm) 85.0 (78.0-98.5) 83.0 (75.5-92.5) 81.0 (74.0-92.0) 88.0 (79.5-98.5) 82.0 (73.0-91.0)
Hip circumference (cm) 104.0 (97.0-110.5) 101.0 (96-109.5) 99.0 (94.0-110.0) b 105.0 (100.0-110.5) 101.0 (95.0-107.8)
Wrist circumference (cm) 15.5 (15.0-16.5) 15.5 (15.0-16.2) 15.2 (14.5-16.0) 15.8 (15.2-16.5) 15.5 (15.0-16.2)
Systolic Blood Pressure (mmHg) 102.5 (98.0-111.3) 100.0 (90.3-112.3) 106.0 (98.0-112.3) 106.5 (98.3-116.8) 106.0 (98.0-114.0)
Diastolic Blood Pressure (mmHg) 70.0 (65.0-75.0) 70.0 (68.8-81.3) 72.0 (68.8-81.3) 71.5 (65.0-77.0) 71.0 (64.0-76.0)
FBS 87.0 (81.5-91.5) 101.0 (96.0-109.5) 86.0 (81.0-89.0) 87.0 (81.3-95.0) 86.0 (81.0-92.0)
TT a 0.5 (0.3-0.7) 0.5 (0.4-0.8) c 0.4 (0.3-0.8) d 0.3 (0.2-0.4) 0.4 (0.2-0.6)
SHBG b, e 37.0 (27.0-43.0) b, f 58.0 (46.0-106.0) 36.0 (25.0-41.0) b, d 38.0 (28.0-45.0) 45.5 (39.0-54.8)
FAI a, b, e 3.4 (2.2-3.8) f 2.1 (2.0-4.4) c 5.1 (3.2-7.7) 2.4 (1.9-3.6) 2.4 (1.5-4.2)
DHEAS 119.0 (77.0-162.3) 122.0 (85.7-139.2) c 180.0 (123.0-221.8) 96.0 (64.0-130.0) 124.0 (75.5-145.3)
A4 b 1.4 (0.6-2.3) 1.1 (0.3-1.4) 1.5 (0.9-2.7) 1.1 (0.5-1.6) 0.8 (0.5-1.7)
  1. PCOS, polycystic ovary syndrome using NIH definition; CH, clinical hyperandrogenism; BH, biochemical hyperandrogenemia; IH, idiopathic hirsutism; Normal group, eumenorrheic without hirsutism. BMI, body mass index; DHEAS, Dehydroepiandrosterone sulfate; Total T, Total testosterone; A4, Androstendion; SHBG, Sex Hormone Binding Globulin; FAI, Free androgen index
  2. Values are given as median (Inter quartile range), a = Group 1 vs. Group 4; b = vs. normal group, p < 0.001, c = Group 3 vs. Group 4, p < 0.001; d = Group 2 vs. Group 4, p < 0.001; e = Group1 vs. Group 2, p < 0.001; f = Group 2 vs. Group 3, p < 0.001
  3. The hormonal profile of women on hormonal therapy (n = 31) were excluded from statistical analysis.