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Table 1 Results of the IMSI vs. ICSI procedure in couples with poor embryo development - all embryos arrested following a prolonged 5-day culture in previous cycles of ICSI.

From: The IMSI procedure improves poor embryo development in the same infertile couples with poor semen quality: A comparative prospective randomized study

 

Method of in vitrofertilization

IVF outcome parameters

IMSI group

ICSI group

 

previous

ICSI

current

IMSI

previous

ICSI

current

ICSI

No. of couples

20

20

37

37

Average female age (years)

34.7 ± 4.02

35.8 ± 4.36

32.0 ± 4.04

32.9 ± 4.48

No. of injected oocytes (%)

158 (74.9%)

121 (75.1%)

227 (80.2%)

235 (79.3%)

No. of fertilized oocytes (zygotes) (%)

86 (54.4%)

62 (51.2%)

129 (56.8%)

124 (52.7%)

No. of triploid zygotes (%)

3 (1.9%)

0 (0%)

3 (1.1%)

3 (1.2%)

Average no. of embryos per cycle

2.6 ± 6.21

3.1 ± 3.45

2.8 ± 6.94

3.3 ± 3.29

No. of blastocysts (%)

0 (0%)

16 (26.0%)

0 (0%)

24 (19.3%)

No. of blastocysts pr cycle

0

0.80

0

0.65

No. of arrested embryos - morula (%)

26 (30.2%)

17 (27.4%)

41 (31.7%)

25 (19.1%)

No. of embryos arrested prior to the morula stage (%)

44 (51.2%)

29 (47.0%)

88 (68.2%)

75 (60.5%)

No. of cycles with at least one blastocyst (%)

0 (0%)

10 (50.0%)

0 (0%)

13 (35.1%)

No. of cycles with all embryos arrested (%)

33 (100%)

0 (0%) a

46 (100%)

10 (27.0%) b

Implantation rate

0%

17.1% (6/35)

0%

6.8% (3/44)

No. of pregnancies

0

5

0

3

Pregnancy rate per cycle

0%

25.0%

0

8.1%

  1. Values are average ± SD
  2. a vs. b statistically significant difference as evaluated by the chi-square test (p < 0.05)