Ovarian sensitivity index is strongly related to circulating AMH and may be used to predict ovarian response to exogenous gonadotropins in IVF

Table 2 Clinical characteristics of patients subgrouped according to circulating AMH levels

	Subgroup A n = 14	Subgroup B n = 13	Subgroup C n = 18	Subgroup D n = 16	p	Significant comparisons
MH (ng/ml)	0.25-1.1	1.2-1.6	1.7-2.6	2.7-8.5
Age (years)	35.8 ± 2.9	34.7 ± 3.7	34.8 ± 3.7	34.1 ± 3.8	0.64
BMI (Kg/m ² )	22.7 ± 3.4	21.7 ± 1.9	22.8 ± 3.0	22.8 ± 3.2	0.69
AFC	10.3 ± 3.3	12.3 ± 3.6	14.6 ± 4.0	22.8 ± 6.9	0.0001*	D vs. A, B, C
Total dose of rFSH (IU)	3255 ± 1058	2418 ± 866	2347 ± 1066	1525 ± 527	0.0001*	D vs. A, B, C
Stimulation length (days)	12.5 ± 1.7	11.0 ± 1.2	11.7 ± 1.8	11.7 ± 2.0	0.17
N. of retrieved oocytes	7.0 ± 3.0	8.6 ± 3.3	10.5 ± 4.9	11.8 ± 4.7	0.02*	A vs .D
Ovarian sensitivity index (IU)	798 ± 1128	337 ± 216	304 ± 319	153 ± 92	0.0001*	D vs. A, B, C

Subgroup A: below the 25^th percentile (AMH 0.25-1.1 ng/ml); Subgroup B: between 25^th and 50^th percentiles (AMH 1.2-1.6 ng/ml); Subgroup C: between 50^th and 75^th percentiles (AMH 1.7-2.6 ng/ml); Subgroup D: above the 75^th percentile (AMH 2.7-8.5 ng/ml).

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