Arsenic abrogates the estrogen-signaling pathway in the rat uterus

Table 3 Luminal diameter, height of luminal epithelial cells, diameter of endometrial glands and width of longitudinal muscles in different experimental groups of adult female rats

Treatment	Luminal diameter (μm)^#	Height of luminal epithelial cells (μm)^§	Diameter of endometrial glands (μm)^§	Width of longitudinal muscle layer (μm)^§
Control	45.88 ± 1.87	18.44 ± 0.19	58.95 ± 3.04	75.89 ± 0.68
4 μg/ml NaAsO₂	10.72 ± 0.51**	5.7 ± .04***	16.61 ± 0.44**	37.69 ± 1.6**

Histological analysis was carried out for each control and arsenic-treated rat, and the uterine parameters were measured by occulometry. Each value represents mean ± SE, n = 5. (ANOVA followed by multiple Students' t-tests, ** p < 0.01, *** p < 0.001, as compared with respective controls). ^# Magnification: 10×; ^§ magnification: 40×.

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