|
n
|
20
|
20
| |
|
Median (range) age (yrs)
|
32.5 (20 - 43)
|
31.0 (24-41)
|
0.8
|
|
Mean (SE) birth weight (g)
|
3040 (206)
|
3364 (216)
|
0.15
|
|
Infant birth weight < 2500 g, n (%)
|
7 (35)
|
3 (15)
|
0.15
|
|
Small for gestational age (birth weight < 10th centile)
|
5 (25%)
|
0
|
0.048
|
|
Mean (SE) serum MMP-1 levels in ng/ml
| | | |
|
6-8 wks
|
346 (36)
|
438 (104)
|
0.35
|
|
10-12 wks
|
355 (52)
|
366 (55)
|
0.69
|
|
20 wks
|
337 (29)
|
380 (71)
|
0.55
|
|
34 wks
|
524 (52)
|
529 (104)
|
0.97
|
|
Cord serum
|
375 (41)
|
476 (115)
|
0.36
|
|
Mean (SE) serum MMP-3 levels in ng/ml
| | | |
|
6-8 wks
|
5.6 (0.7)
|
3.2 (0.4)
|
0.01
|
|
10-12 wks
|
7.4 (2.4)
|
5.2 (0.7)
|
0.39
|
|
20 wks
|
5.3 (0.7)
|
5 (0.7)
|
0.74
|
|
34 wks
|
4.7 (0.6)
|
5 (0.6)
|
0.64
|
|
Cord serum
|
1.8 (0.4)
|
1.8 (0.4)
|
0.90
|
|
Mean (SE) serum MMP-9 levels in ng/ml
| | | |
|
6-8 wks
|
70.0 (6.9)
|
86.0 (15.3)
|
0.31
|
|
10-12 wks
|
91.5 (10.3)
|
83.3 (13.0
|
0.62
|
|
20 wks
|
105.8 (12.4)
|
80.6 (12.8)
|
0.15
|
|
34 wks
|
89.4 (11.3)
|
111.8 (14.6)
|
0.23
|
|
Cord serum
|
47.6 (8.7)
|
51.7 (7.4)
|
0.72
|
|
Mean (SE) serum TIMP-1 levels in ng/ml)
| | | |
|
6-8 wks
|
20.0 (2.0)
|
17. 1 (2.4)
|
0.37
|
|
10-12 wks
|
23.7 (1.8)
|
20.6 (3.5)
|
0.42
|
|
20 wks
|
23.9 (2.8)
|
23.3 (2.7)
|
0.88
|
|
34 wks
|
18.4 (2.1)
|
18.9 (2.4)
|
0.87
|
|
Cord serum
|
17.9 (2.7)
|
21.7 (3.0)
|
0.35
|
|
Mean (SE) serum TIMP-2 levels in ng/ml
| | | |
|
6-8 wks
|
36.0 (8.4)
|
13.8 (1.4)
|
0.01
|
|
10-12 wks
|
31.0(5.2)
|
11.7 (1.1)
|
0.002
|
|
20 wks
|
23.6 (5.2)
|
9.9 (0.9)
|
0.008
|
|
34 wks
|
23.7 (3.2)
|
16.9 (1.3)
|
0.05
|
|
Cord serum
|
16.7 (6.1
|
11.1 (1.1)
|
0.44
|
|
Relaxin:TIMP-2 ratio*
| | | |
|
6-8 wks
|
0.05 (0.01)
|
0.18 (0.03)
|
0.006
|
|
10-12 wks
|
0.05 (0.01)
|
0.17 (0.03)
|
0.0001
|
|
20 wks
|
0.03 (0.01)
|
0.08 (0.02)
|
0.03
|
|
34 wks
|
0.04 (0.01)
|
0.13 (0.02)
|
0.02
|
|
Cord serum
|
0.01 (0.01)
|
0.00 (0.00)
|
0.13
|
