Species | Stressor | Hormone treatment | LH release | References |
---|---|---|---|---|
Rats | 1-h or 10-min immobilization | Estradiol vs no hormone treatment | Positive | |
 | Rapid blood volume depletion | Estradiol+progesterone+thyroxine vs no hormone treatment | Positive | [66] |
 | Transfer to a novel environment followed by a return to the original quarters 30 min later, or 15-min exposure to strobe light | No hormone treatment vs estradiol | Positive | [72] |
Rhesus monkeys | 30-min intracerebroventricular infusion of interleukin-1α | Estradiol at doses that result in plasma estradiol levels that reproduce the late follicular phase | Positive | [56] |
 |  | Estradiol at doses that result in plasma estradiol levels that reproduce the early-mid follicular phase | No effect | [57] |
Women | Single intravenous injection of endotoxin | Estradiol vs no hormone treatment | Positive | [35] |