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Table 1 Summary of estrous cycles recorded during 8 days, shortly after the conclusion of chemotherapy course.

From: Assessment of fertility protection and ovarian reserve with GnRH antagonist in rats undergoing chemotherapy with cyclophosphamide

  Group I
(placebo)
Group II
(CPA)
Group III
(GnRHant + CPA)
Group IV
(GnRHant)
Chi-Square
(p value)
Number of surviving rats per group 9 10 12 9 -
Number of rats with a cyclic pattern (%) 9
(100)
9
(90)
11
(92)
9
(100)
2.50
(p = 0.48)
Number of rats with estrus/proestrus (%) 9
(100)
5
(50)
10
(83)
9
(100)
12.42
(p < 0.01)
  1. CPA, cyclophosphamide; GnRHant, gonadotropin-releasing hormone antagonist (cetrorelix).