| Group IIα (normal weight controls) (n = 25) | Group IIβ (overweight/obese controls) (n = 25) | p (adjusted for age) |
---|---|---|---|
Age (years) | 31.3 ± 4.5 | 33.9 ± 4.6 | NA |
BMI (kg/m2) | 21.9 ± 1.6 | 28.3 ± 3.0 | < 0.001 |
Waist (cm) | 73.7 ± 5.6 | 87.9 ± 8.5 | < 0.001 |
FSH (mIU/ml) | 8.1 ± 2.5 | 7.8 ± 3.2 | NS |
LH (mIU/ml) | 7.1 ± 3.3 | 4.8 ± 1.5 | 0.011 |
Prolactin (ng/ml) | 12.1 ± 3.8 | 12.4 ± 4.7 | NS |
Testosterone (ng/dl) | 36.4 ± 14.5 | 29.4 ± 13.8 | NS |
Δ4-A (ng/ml) | 1.8 ± 0.4 | 1.7 ± 0.6 | NS |
DHEA-S (ng/ml) | 2138.9 ± 788.6 | 1750.4 ± 803.1 | NS |
FAI | 1.89 ± 0.99 | 2.07 ± 1.31 | NS |
17α-OHP (ng/ml) | 0.7 ± 0.3 | 0.7 ± 0.3 | NS |
SHBG (nmol/l) | 76.4 ± 30.8 | 61.9 ± 35.5 | NS |
Glucose (mg/dl) | 95.1 ± 7.8 | 98.9 ± 11.2 | NS |
Insulin (μIU/ml) | 8.2 ± 7.0 | 10.3 ± 6.6 | NS |
Glucose/insulin | 15.48 ± 7.27 | 14.23 ± 10.62 | NS |
HOMA-IR | 1.96 ± 1.76 | 2.53 ± 1.63 | NS |
QUICKI | 0.36 ± 0.03 | 0.35 ± 0.04 | NS |
Area under the OGTT curve | 13009.8 ± 1680.8 | 16121.4 ± 3883.3 | 0.002 |
Mean ovarian volume (cm3) | 5.3 ± 1.9 | 5.3 ± 1.8 | NS |
Mean number of ovarian follicles | 6.0 ± 1.9 | 6.4 ± 1.9 | NS |
Lipocalin (ng/ml) | 50.5 ± 23.7 | 70.1 ± 24.9 | 0.004 |