Table 2 Anthropometric, hormonal, metabolic and ultrasonographic characteristics of normal weight and overweight/obese patients with polycystic ovary syndrome (PCOS).
|  | Group Iα (normal weight patients with PCOS) (n = 100) | Group Iβ (overweight/obese patients with PCOS) (n = 100) | p (adjusted for age) |
|---|---|---|---|
Age (years) | 23.4 ± 4.5 | 25.7 ± 5.8 | NA |
BMI (kg/m2) | 22.1 ± 1.8 | 31.9 ± 5.6 | < 0.001 |
Waist (cm) | 72.8 ± 5.3 | 94.2 ± 13.6 | < 0.001 |
FSH (mIU/ml) | 6.8 ± 1.9 | 6.0 ± 1.7 | 0.001 |
LH (mIU/ml) | 8.5 ± 5.5 | 6.7 ± 4.4 | 0.025 |
Prolactin (ng/ml) | 14.7 ± 6.6 | 13.9 ± 7.3 | NS |
Testosterone (ng/dl) | 74.7 ± 27.3 | 75.4 ± 32.7 | NS |
Δ4-A (ng/ml) | 2.9 ± 1.1 | 2.9 ± 0.9 | NS |
DHEA-S (ng/ml) | 3148.6 ± 1218.2 | 3063.1 ± 1384.1 | NS |
FAI | 5.80 ± 4.19 | 9.51 ± 7.19 | < 0.001 |
17α-OHP (ng/ml) | 1.1 ± 0.5 | 1.1 ± 0.5 | NS |
SHBG (nmol/l) | 59.0 ± 30.5 | 35.2 ± 19.4 | < 0.001 |
Glucose (mg/dl) | 94.9 ± 10.0 | 102.1 ± 28.3 | NS |
Insulin (μIU/ml) | 8.6 ± 5.0 | 16.1 ± 10.6 | < 0.001 |
Glucose/insulin | 13.68 ± 6.02 | 9.36 ± 6.61 | < 0.001 |
HOMA-IR | 2.04 ± 1.34 | 4.38 ± 5.08 | < 0.001 |
QUICKI | 0.35 ± 0.03 | 0.32 ± 0.03 | < 0.001 |
Area under the OGTT curve | 14496.9 ± 2725.9 | 15797.4 ± 3388.2 | 0.006 |
Mean ovarian volume (cm3) | 7.7 ± 3.7 | 11.9 ± 5.0 | < 0.001 |
Mean number of ovarian follicles | 10.9 ± 5.2 | 10.8 ± 4.1 | NS |
Lipocalin (ng/ml) | 54.5 ± 27.2 | 76.2 ± 37.3 | < 0.001 |