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Figure 4 | Reproductive Biology and Endocrinology

Figure 4

From: Epigenetic regulation of CD133 and tumorigenicity of CD133 positive and negative endometrial cancer cells

Figure 4

Serial transplantation does not generate significant genomic alterations in endometrial tumors. The integrity of the genome was assessed in the first, third and sixth serially transplanted xenograft tumors derived from endometrioid endometrial tumor sample T6 by array comparative genomic hybridization (aCGH). As shown, the genomic profiles remain virtually unchanged across the transplant process. Arrows indicate regions of increased and decreased DNA copy numbers detected on chromosomes 1-22 and the X chromosome.

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