Figure 1From: Effect of chronic treatment with Rosiglitazone on Leydig cell steroidogenesis in rats: In vivo and ex vivo studiesEx vivo production of testosterone in Leydig cells isolated from control or rosiglitazone-treated (RSG-treated) rats; Leydig cells (0.3 × 106/0.5 ml) were incubated for 2 h with M199, hCG (1 mIU/ml), dbcAMP (1 mM), 22-OH-C (10 μM) or pregnenolone (1 μM). Results are the mean ± SEM of three determinations; *p < 0.001 (ANOVA).Back to article page