Figure 1

ADAM12 concentration in serum is dependent on Maternal Weight. Log ADAM12-S concentration (μg/l) in maternal serum from 645 controls by gestation (top panel) and by weight (bottom panel). The superimposed lines correspond to the fitted relationship from the multiple regression model log ADAM12-S = 2.9530 + 0.01454 (gestational age (days) - 77) - 0.002421 (maternal weight - 69). The median maternal weight (67 kg) and median gestational age (66 days) have been used to obtain the fitted lines on the top and bottom panels respectively.