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Figure 1 | Reproductive Biology and Endocrinology

Figure 1

From: A cross-study gene set enrichment analysis identifies critical pathways in endometriosis

Figure 1

Significant pathways identified and overlap between the 3 ovarian endometriosis data sets. For each data set, GSEA implanted to generate p-values for each pathway and using a permutation test with 1000 times, obtained the significant pathways with p-value cut-off of ≤ 0.05. (a) GSEA detected 24 (Eyster data set), 56 (Hever data set) and 36 (Roth data set) up-regulated pathways and 16 are common. (b) GSEA detected 31 (Eyster data set), 59 (Hever data set) and 44(Roth data set) down-regulated pathways and 19 are common.

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