Prolactin signaling through the short isoform of the mouse prolactin receptor regulates DNA binding of specific transcription factors, often with opposite effects in different reproductive issues

Table 3 List of transcription factors by functional category

A. Growth and Differentiation
Decidua		Ovary
Myb	Activated	C/EBPalpha	Activated
ODC	Activated	c-Myb	Activated
Pax1	Activated	EGR1	Inhibited
RUNX1	Activated	HIF-1	Activated
PRDII-BF1	Activated	NZF-3	Activated
RFX1/2/3	Activated	TFIID	Activated
TEF1	Activated
TFEB	Activated
AP-2	Inhibited
c-Myb BP	Inhibited
HIF-1	Inhibited
MT-Box	Inhibited
MTF-1	Inhibited
RAR (DR-5)	Inhibited
B.Development and Steroidogenesis
Decidua		Ovary
CTCF	Inhibited	Cdx2	Inhibited
HFH-3	Inhibited	COUP-TF	Activated
HOXD8,9,10	Activated	EKLF	Activated
Pax6	Activated	GATA-4	Activated
Pax8	Activated	MZF1	Activated
		Pax4	Activated
		Pax6	Activated
C. Immune Response
Decidua		Ovary
Pax5	Activated	AML1	Activated
CDP	Inhibited	GRE	Activated
NFIL-2	Inhibited	LyF-1	Activated
RORE	Inhibited	NFAT	Activated
		Pax5	Activated
D. Inflammation/Stress
Decidua		Ovary
Foxo4	Activated	Foxo4	Inhibited
NFkB	Activated	NFkB	Inhibited
Sp1	Inhibited	Sp1	Inhibited
		E4BP4	Inhibited
E. Glucose Metabolism
Ovary
ADR1	Activated
ANG-IRE	Activated
MUSF1	Activated
PTF1	Activated
RIPE3a1	Activated
L-III BP	Inhibited

ISSN: 1477-7827