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Table 2 Comparison of androstenedione 17-hydroxyprogesterone, testosterone and progesterone levels 2 weeks after lentivirus injection.

From: Study of RNA interference inhibiting rat ovarian androgen biosynthesis by depressing 17alpha-hydroxylase/17, 20-lyase activity in vivo

Ovarian hormones

CON

(ng/ml)

n = 6

NC

(ng/ml)

n = 6

2#

(ng/ml)

n = 6

Androstenedione

0.43 ± 0.19

0.94 ± 0.012

0.33 ± 0.076

17-hydroxyprogesterone

2.56 ± 0.44

1.94 ± 0.18

1.76 ± 0.13

Testosterone

3.14 ± 0.23

3.63 ± 0.23

2.85 ± 0.13

Progesterone

31.52 ± 2.96

34.98 ± 2.68

20.41 ± 1.02*

  1. Values are expressed as mean ± SD
  2. *ANOVA, P < 0.05 when compared with both CON and NC groups. CON: Blank Control; NC: Negative Control: 2#: CYP17 shRNA2#.