Figure 4
From: Epigenetic regulation in mammalian preimplantation embryo development
Epigenetic and genetic interactions during early preimplantation development. After fertilization, some maternally-derived epigenetic participants (e.g. DNMTs, Ago2) remain to be involved in gene expression transition(ZGA) and alter the gene expression status, leading to the expression of more epigenetic participants and other genes. These newly expressed ones are then added to further regulate the gene expression and developmental events.