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Figure 6 | Reproductive Biology and Endocrinology

Figure 6

From: Uterine and placental expression of TRPV6 gene is regulated via progesterone receptor- or estrogen receptor-mediated pathways during pregnancy in rodents

Figure 6

Effects of steroid receptor antagonists on uterine and placental TRPV6 mRNA expressions. Panel A (uteri at P5.5) and B (placenta at P20.5) presented the rat TRPV6 mRNA levels. Four groups of pregnant rats (n = 4 per group) were treated with ethanol as a negative control (VE), progesterone receptor antagonist (RU, 2.5 mg per rat), or estrogen receptor antagonist (ICI, 0.5 mg per mouse). Panel C (uteri at P10.5) and D (placenta at P10.5) showed the mouse TRPV6 mRNA expressions. Four groups of pregnant mice (n = 4 per group) were treated with ethanol as a negative control (VE), progesterone receptor antagonist (RU, 25 μg per mouse) or estrogen receptor antagonist (ICI, 2 μg per mouse). Murine TRPV6 mRNA levels were examined by real-time PCR. The bar graph represents the analysis of real-time PCR data expressed as a percentage of TRPV6/HPRT1 (mean ± SEM of duplicates). a, statistically significant compared to a vehicle (P < 0.05).

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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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