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Table 3 Mean age-class adjusted values (SD) of LS-, TH- and FN-BMD regarding ESR1 and ESR2 genotypes.

From: Age-specific effects of estrogen receptors' polymorphisms on the bone traits in healthy fertile women: the BONTURNO study

Age classes 1 2 3
Subjects (n) 158 192 219
Age range (yrs) 20–30 31–40 41–50
BMD (g/cm2) LS TH FN LS TH FN LS TH FN
ESR1 rs2234693          
CC 1.063
(0.134)
0.941
(0.117)
0.859
(0.150)
1.075
(0.138)
0.906
(0.098)
0.821
(0.125)
1.021
(0.122)
0.902
(0.115)
0.778
(0.122)
CT 1.025
(0.112)
0.930
(0.120)
0.845
(0.116)
1.067
(0.122)
0.906
(0.117)
0.795
(0.118)
1.041
(0.127)
0.905
(0.127)
0.789
(0.115)
TT 1.077
(0.131)
0.969
(0.121)
0.874
(0.129)
1.059
(0.106)
0.928
(0.105)
0.813
(0.118)
1.049
(0.125)
0.904
(0.124)
0.777
(0.122)
ESR2 rs4986938          
AA 1.039
(0.130)
0.932
(0.110)
0.846
(0.112)
1.059
(0.123)
0.922
(0.110)
0.814
(0.122)
1.044 (0.147) 0.860 (0.111) 0.738
(0.108)
AG 1.044
(0.126)
0.935
(0.125)
0.847
(0.131)
1.076
(0.117)
0.910
(0.106)
0.804
(0.110)
1.032 (0.128) 0.900 (0.118) 0.784
(0.118)
GG 1.056
(0.121)
0.963
(0.122)
0.870
(0.135)
1.056
(0.125)
0.911
(0.115)
0.806
(0.132)
1.046 (0.115) 0.923 (0.130) 0.798
(0.119)