Age-specific effects of estrogen receptors' polymorphisms on the bone traits in healthy fertile women: the BONTURNO study

Table 3 Mean age-class adjusted values (SD) of LS-, TH- and FN-BMD regarding ESR1 and ESR2 genotypes.

Age classes	1			2			3
Subjects (n)	158			192			219
Age range (yrs)	20–30			31–40			41–50
BMD (g/cm2)	LS	TH	FN	LS	TH	FN	LS	TH	FN
ESR1 rs2234693
CC	1.063 (0.134)	0.941 (0.117)	0.859 (0.150)	1.075 (0.138)	0.906 (0.098)	0.821 (0.125)	1.021 (0.122)	0.902 (0.115)	0.778 (0.122)
CT	1.025 (0.112)	0.930 (0.120)	0.845 (0.116)	1.067 (0.122)	0.906 (0.117)	0.795 (0.118)	1.041 (0.127)	0.905 (0.127)	0.789 (0.115)
TT	1.077 (0.131)	0.969 (0.121)	0.874 (0.129)	1.059 (0.106)	0.928 (0.105)	0.813 (0.118)	1.049 (0.125)	0.904 (0.124)	0.777 (0.122)
ESR2 rs4986938
AA	1.039 (0.130)	0.932 (0.110)	0.846 (0.112)	1.059 (0.123)	0.922 (0.110)	0.814 (0.122)	1.044 (0.147)	0.860 (0.111)	0.738 (0.108)
AG	1.044 (0.126)	0.935 (0.125)	0.847 (0.131)	1.076 (0.117)	0.910 (0.106)	0.804 (0.110)	1.032 (0.128)	0.900 (0.118)	0.784 (0.118)
GG	1.056 (0.121)	0.963 (0.122)	0.870 (0.135)	1.056 (0.125)	0.911 (0.115)	0.806 (0.132)	1.046 (0.115)	0.923 (0.130)	0.798 (0.119)

ISSN: 1477-7827