Excitatory and inhibitory effects of prolactin release activated by nerve stimulation in rat anterior pituitary

Table 4 PRL concentrations of 10-min sampled perfusate, EFS of 10 min (Mean ± SD, pg/ml)

	Group M	Group N	Group O	Group P
-10	119 ± 1.0	119 ± 1.3	120 ± 1.2	120 ± 2.1
0	181 ± 6.1**	114 ± 3.8	110 ± 6.6	114 ± 5.2
10	181 ± 5.1**	117 ± 1.3	88 ± 2.4**	118 ± 1.1
20	179 ± 6.4**	120 ± 3.6	80 ± 0.6**	120 ± 2.4
30	151 ± 7.0**	119 ± 2.0	81 ± 2.3**	120 ± 1.3
40	117 ± 6.0	116 ± 3.7	93 ± 3.3**	117 ± 5.2
50	118 ± 4.2	118 ± 1.5	105 ± 6.3	120 ± 1.1
60	119 ± 3.2	119 ± 3.0	115 ± 3.6	121 ± 4.8
70	119 ± 3.2	119 ± 1.9	116 ± 4.7	121 ±1.7
80	113 ± 4.4	115 ± 3.9	117 ± 4.5	115 ± 4.6
90	118 ± 2.1	117 ± 1.6	119 ± 1.4	119 ± 2.1
K ⁺	542 ± 24.4**	576 ± 18.3**	566 ± 38.9**	604 ± 8.3**
N	6	5	5	5

Group M: 2 Hz. Group N: 2 Hz + TTX (1 μmol/L). Group O: 10 Hz. Group P: 10 Hz + TTX (1 μmol/L).
The perfusate was continuously collected as aliquots every 10 min and measured by RIA. Italic data represents results during electrical field stimulation.
TTX, tetrodotoxin; EFS, electrical field stimulation; N, the number of the rat used.
*Significant changes within group (** P < 0.01).

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