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Figure 6 | Reproductive Biology and Endocrinology

Figure 6

From: Spatio-temporal expression patterns of anandamide-binding receptors in rat implantation sites: evidence for a role of the endocannabinoid system during the period of placental development

Figure 6

Spatial distribution of cannabinoid and vanilloid receptors on day 14 of pregnancy. (A) CB1 expression, in the mesometrial decidua and basal zone of placenta; (B) High magnification of the square depicted in (A); note the positive decidual and endothelial cells. (C) Higher magnification image of the basal zone. The giant trophoblast and spongiotrophoblast cells are positive for CB1; (D) Expression of CB2 is lower than CB1 in the mesometrial decidua and basal zone; (E) Negative control for TRPV1; (F) TRPV1 expression in the mesometrial decidua and basal zone; (G) High magnification of the mesometrial decidua and endovascular trophoblast cells; note the lack of staining for TRPV1 in these trophoblast cells and the presence of apoptotic bodies in the decidua (arrowheads); (H) Expression of TRPV1 is particularly evident in uNK cells in the metrial gland region (arrows). BV - Blood vessel; BZ - Basal zone; ET - Endovascular trophoblast cells; GT - Giant trophoblast cells; MD - Mesometrial decidua; MG - Metrial gland; ST - Spongiotrophoblast cells.

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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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