Figure 4From: The uterine expression of SEC63gene is up-regulated at implantation sites in association with the decidualization during the early pregnancy in miceDetermination of uterine Sec63 mRNA in the mouse by in situ hybridization analysis. In situ hybridization of Sec63 mRNA was performed using digoxigenin-labeled anti-sense probes generated against Sec63 cDNA in the mouse uterus on day 1(A) and day 4 (B) of pregnancy; at the implantation site of day 5(C), day 6 (D) and day 8 (E); at the inter-implantation site of day 6 (H); in the uterus of day 5 pseudopregnant mouse (G); delayed implantation (I) before and (J) after activation. (F) is the same as (E), but sense sequence was used for substitution as control. L: lumen of uterus; G: gland; SC: stromal cells; DC: decidual cells; EM: embryo. Scale bars represents 50 μm.Back to article page