Table 1 Morphometric analyses of testes in hpg mice after treatment with estradiol and/or rhFSH

N

3

4

4

5

5

body wt (g)

29.7 ± 3.2

30.0 ± 2.5

29.5 ± 2.5

29.8 ± 2.8

29.0 ± 3.2

testis wt (mg)

12.0 ± 0.1

24.2 ± 1.8^a

27.2 ± 3.3^a

27.2 ± 1.7^a

46.6 ± 4.8^abc

tubule diameter (μm)

50.3 ± 0.7

71.6 ± 3.3^a

66.3 ± 1.6^a

72.3 ± 2.2^a

77.3 ± 3.5^a

tubule volume (μl)

3.8 ± 0.7

11.2 ± 1.1^a

12.1 ± 0.39

12.2 ± 1.1^a

21.8 ± 2.3^abc

tubule length (m)

2.2 ± 0.4

2.8 ± 0.2

3.3 ± 0.2

3.0 ± 0.2

4.6 ± 0.3^abc

tubule (% testis)

76.9 ± 9.9

91.3 ± 1.4

92.5 ± 0.8^a

87.9 ± 1.5

94.0 ± 0.7^a

sem epith vol (μl)

3.6 ± 0.6

9.9 ± 0.9^a

11.0 ± 0.2^a

10.5 ± 0.9^a

19.4 ± 2.0^abc

lumen volume (μl)

0.1 ± 0.1

1.3 ± 0.3

1.6 ± 0.3

1.1 ± 0.1

2.4 ± 0.4