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Figure 6 | Reproductive Biology and Endocrinology

Figure 6

From: THG113.31, a specific PGF2alpha receptor antagonist, induces human myometrial relaxation and BKCa channel activation

Figure 6

Effects of THG113.31 on spontaneous myometrial contractions. A Representative recordings of spontaneous contractions of pregnant human myometrium under control conditions and (B) the effects of cumulative additions of THG113.31 (1 nM, 10 nM, 100 nM, 1 μM and 10 μM) at 20 min intervals are shown. (C & D) The uterorelaxant effect was significantly attenuated by pre-incubation with the BKCa channel antagonist, IbTX

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