Skip to main content
Figure 3 | Reproductive Biology and Endocrinology

Figure 3

From: Role of nonhuman primate models in the discovery and clinical development of selective progesterone receptor modulators (SPRMs)

Figure 3

Spectrum of progesterone agonist and antagonist activities of major 11β-benzoxime-substituted SPRMs and PAs. The figure is based on studies in rabbits (McPhail test) and guinea pigs (luteolysis inhibition assay, induction of labor). ONA, onapristone; R520, pure progestin promegestone; J867, asoprisnil; PR, progesterone receptor. From [54] with permission.

Back to article page