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Table 1 Summary of data published about the role of 3D-ultrasound for assessing normal menstrual cycle

From: Three-dimensional ultrasound assessment of endometrial receptivity: a review

Author n Primary Outcome 3D Method Study Design Findings
Lee (45) 18 Uterine-Endometrial volume ratio Multislice Longitudinal at 3–6 days interval Uterine-Endometrial volume ratio decrease throughout menstrual cycle (R2 = 0.4318)
Raine-Fenning (46) 30 Endometrial volume VOCAL Longitudinal at 2 days interval in follicular phase and 4 days interval in luteal phase Endometrial volume increase steadily during follicular phase, plateauing during luteal phase
Raine-Fenning (47) 27 Endometrial and subendometrial vascularity VOCAL Longitudinal at 2 days interval in follicular phase and 4 days interval in luteal phase Endometrial and subendometrial VI/FI/VFI increased from mid-follicular phase peaking 3 days prior to ovulation and then decrease until 5 days postovulation, increasing then again until the next cycle
Jokubkiene (50) 16 Endometrial volume, and endometrial and subendometrial vascularity VOCAL Longitudinal, daily in follicular phase and 2 days interval in luteal phase Endometrial and subendometrial VI/FI/VFI increased from mid-follicular phase peaking 2 days prior to ovulation and then decrease until 2 days after ovulation, increasing then again until the next cycle