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Figure 1 | Reproductive Biology and Endocrinology

Figure 1

From: Possible involvement of integrin-mediated signalling in oocyte activation: evidence that a cyclic RGD-containing peptide can stimulate protein kinase C and cortical granule exocytosis in mouse oocytes

Figure 1

Effects of a cyclic RGD peptide on sperm-oocyte fusion. ZP-free mouse oocyte were incubated in the presence of different concentrations of cyclic RGD or nonRGD peptides for 30 min prior to fertilization. Oocytes were then inseminated with 1–5 × 104 sperm/ml in the presence of peptide. The results here represent the average of 3 experiments per peptide concentration ± S.E.M. and a total of 60–80 inseminated oocytes per experimental point. Means with different letters are statistically different (P < 0.05).

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