Table 3 Outcome of stimulation in normoovulatory patients with unexplained infertility and comparison between HP-uFSH and r-FSH (* values are expressed as mean ± SD; ns = not significant).
| Â | Overall | HP-uFSH | rFSH | P |
|---|---|---|---|---|
N. of patients | 184 | 91 | 93 | Â |
N. of stimulation cycles | 184 | 91 | 93 | Â |
Total FSH dose (IU) * | 762 ± 505 | 837 ± 349 | 644 ± 199 | 0.005 |
Duration of follicular phase (days) * | 12.0 ± 2.9 | 12.4 ± 2.5 | 11.6 ± 2.1 | ns |
No. of preovulatory follicles ≥ 18 mm at hCG * | 1.2 ± 0.9 | 1.2 ± 0.8 | 1.1 ± 0.9 | ns |
No. of follicles 12–17 mm at hCG * | 0.4 ± 0.3 | 0.4 ± 0.3 | 0.4 ± 0.3 | ns |
Size of the dominant follicle at hCG (mm) * | 20.5 ± 1.9 | 20.6 ± 1.8 | 20.4 ± 1. 8 | ns |
Endometrial thickness at hCG (mm) * | 9.5 ± 2.0 | 9.6 ± 1.9 | 9.5 ± 1.5 | ns |
Monofollicular cycles (%) | 150 (81.5) | 74 (81.3) | 76 (81.7) | ns |
Bi-/trifollicular cycles (%) | 20 (10.9) | 10 (11.0) | 10 (10.8) | ns |
Cancelled cycles (%) | 14 (7.6) | 7 (7.7) | 7 (7.5) | ns |
Deliveries | 19 | 9 | 10 | Â |
Delivery rate/started cycle (%) | 10.3 | 9.9 | 10.7 | ns |
Delivery rate/ovulatory cycle (%) | 11.2 | 10.7 | 11.6 | ns |