Table 1 Ovarian weights in rats injected with a low, middle and a high dose of the Reference Standard, Bravelle®, Menopur®, or a mixture of Bravelle® and Menopur® reconstituted in 0.9% saline and mixed in the same syringe.
Hormone (FSH:LH)a | Total no. rats | Ovarian weights (mean ± SEM)b* | ||
|---|---|---|---|---|
| Â | Â | Lowc dose | Middled dose | Highe dose |
Reference Standard | 48 | 93.55 ± 4.17 | 151.37 ± 4.00 | 193.01 ± 5.02 |
Bravelle® (75:0) | 48 | 92.31 ± 3.02 | 149.60 ± 3.29 | 201.37 ± 4.56 |
Menopur® (75:75) | 48 | 92.19 ± 3.45 | 151.51 ± 2.62 | 194.92 ± 4.03 |
Bravelle® + Menopur® | ||||
(150:75) | 48 | 97.29 ± 2.80 | 148.82 ± 3.65 | 199.59 ± 4.30 |
(300:75) | 48 | 92.38 ± 3.37 | 157.08 ± 3.82 | 192.62 ± 5.50 |
(300:225) | 48 | 95.75 ± 2.94 | 149.50 ± 6.11 | 195.39 ± 6.13 |