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Table 3 In labour group compared with not in labour group. In labour group includes preterm labour (PTL) and term labour (TL) groups, not in labour group includes preterm not in labour (PTnotL) and term not in labour (TnotL) groups. Protein concentrations are expressed in pg/mg of total protein. Expression of mRNA is the product/28S intensity ratio. Significant differences between the groups were determined using Mann-Whitney U Test. NS-statistically not significant difference.

From: Non-infected preterm parturition is related to increased concentrations of IL-6, IL-8 and MCP-1 in human cervix

Measured factor

In Labour Group (PTL and TL)

Not in Labour Group (PTnotL and TnotL)

p value

 

Median

Min

Max

N

Median

Min

Max

N

 

IL-6 protein

396.7

7.7

1286.4

28

5.9

2.1

215.0

18

<0.0001

IL-8 protein

818.9

13.9

1288.1

28

71.0

4.8

1278.9

19

<0.0001

MCP-1 protein

420.8

21.2

1293.5

28

39.5

15.4

598.7

19

<0.0001

TNF-α protein

4.6

0.8

31.4

18

3.5

1.7

7.8

10

NS

RANTES protein

576.5

165.25

1075.3

18

439.5

141.0

869.6

10

NS

IL-8 mRNA

0.4

0

8.9

31

0

0

0.1

18

<0.0001

MCP-1 mRNA

1.9

0

67.2

31

0.4

0

1.4

18

<0.0001

RANTES mRNA

1.3

0

54.0

31

1.1

0.03

13.8

18

NS

WBC

15.9

7.3

28.4

21

9.6

6.9

14.1

14

<0.001

CRP

13.0

6.9

123.0

18

7.5

6.9

17.0

8

0.0221