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Table 2 Summary of the Effects of IL-1 α and IL-1β on Sertoli and Leydig Cells

From: The role of tumor necrosis factor-alpha and interleukin-1 in the mammalian testis and their involvement in testicular torsion and autoimmune orchitis

Effects of IL-1α on Sertoli Cells

Effects of IL-1β on Leydig Cells

increase proliferation [68]

decrease testosterone [69–71, 74]

 

increase testosterone [72, 73]