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Table 2 Controlled ovarian stimulation (COS) characteristics for assisted reproductive technology cycles overall and by age subgroups

From: A large, multicentre, observational, post-marketing surveillance study of the 2:1 formulation of follitropin alfa and lutropin alfa in routine clinical practice for assisted reproductive technology

COS variable (mean [SD])a

Age subgroup

All patients (n = 2220)b

≤35 years (n = 692)

>35 years (n = 1528)

Duration of COS, days

11.0 (3.36) (n = 690)

10.7 (2.67) (n = 1527)

10.8 (2.90) (n = 2217)

Dose c on first day of COS, IU

163.1/81.6 [= 244.7] (65.37/32.68 [= 98.05]) (n = 567)

192.0/96.02 [= 288.1] (80.71/40.36 [= 121.07]) (n =1258)

183.1/91.5 [= 274.6] (77. 4/38.7 [= 116.1]) (n = 1825)

Dose c on last day of COS, IU

168.11/84.06 [= 252.17] (71.12/35.56 [= 106.68]) (n = 531)

187.89/93.95 [= 281.84] (85.99/42.99 [= 128.98]) (n = 1199)

181.8/90.9 [= 272.7] (82. 2/41.1 [= 123.3]) (n = 1730)

Total dose c required, IU

1617.2/808.6 [= 2425.8] (995.3/497.6 [= 1492.9]) (n = 648)

2064.2/1032.1 [= 3096.3] (1115.4/557.7 [= 1673.1]) (n = 1409)

1923.4/961.7 [= 2885.1] (1098.6/549.3 [= 1647.9]) (n = 2057)

  1. aThe number of cycles for which each COS variable was reported varied.
  2. bThe total number of cycles reported in this study was 2220; however, the duration of COS was unavailable for three cycles.
  3. cDose of the 2:1 formulation of follitropin alfa and lutropin alfa.
  4. SD = standard deviation.
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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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