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Table 3 Embryos kinetics during development to day 5

From: Analysis of embryo morphokinetics, multinucleation and cleavage anomalies using continuous time-lapse monitoring in blastocyst transfer cycles

  Blasts transferred (BL-T) Mean ± SD 95% CI Blasts frozen (BL-F) Mean ± SD 95% CI PQ BL/Non blasts (PQ-D) Mean ± SD 95% CI p
tPNf 24.8 ± 2.6 24.3- 25.3 25.2 ± 3.0 24.9 - 25.6 26.8 ± 8.3 26.6 - 28.0 0.001
t2 27.2 ± 3.6 26.5 - 27.8 27.7 ± 4.0 27.1-28.2 30.0 ± 8.8 28.8- 31.2 <0.0001
t3 37.6 ± 5.5 36.5-38.7 38.0 ± 5.8 37.4 - 38.6 38 ± 11.8 36.4- 39.6 ns
t4 40.0 ± 5.4 39.0 - 41.1 40.9 ± 6.1 40.3- 41.6 43.4 ± 1 4.3 41.4 - 45.4 0.003
t5 52.0 ± 6.3 50.8 - 53.2 52.4 ± 9.0 51.5 - 53.4 50.2 ± 15.3 48.0 - 52.4 ns
t8 62.1 ± 9.8 60.2- 64.0 63.8 ± 11.7 62.6- 65.1 71.1 ± 21.2 67.8 - 74.3 <0.0001
t9+ 73.5 ± 10.3 71.4-75.6 74.7 ± 13.3 73.2-76.3 83.7 ± 24.5 79.7-87.8 <0.0001
tMor 93.9 ± 9.8 91.9 - 95.9 98.2 ± 12.8 96.8 - 99.7 110.7 ± 15.3 106.7 - 114.7 <0.0001
tSB 100.2 ± 7.4 99.0– 101.5 105.5 ± 10.3 104.5 – 106.5 113.1 ± 13.1 110.2 – 116.1 <0.001
tBL 105.2 ± 6.3 103.8 - 106.6 111.1 ± 10.5 109.9 - 112.3 121.4 ± 9.1 116-126.0 <0.0001
tEBL 110.0 ± 5.6 108.6 - 111.4 118.9 ± 12.1 117.3 - 120.4 133.1 ± 9.0 127.1-139.2 <0.0001
cc2 (t3-t2) 10.4 ± 4.5 9.6- 11.3 10.2 ± 4.7 9.7- 10.8 8.6 ± 10.7 7.1 - 10.1 0.02
cc3 (t5-t3) 14.4 ± 5.4 13.4-15.4 14.4 ± 7.3 13.6-15.1 14.0 ± 13.1 12.1-15.8 ns
S1 (t2-tPNf) 2.4 ± 1.7 2.0 – 2.7 2.6 ± 1.9 2.4 -2.8 3.2 ± 3.9 2.6 – 3.7 0.03
s2 (t4-t3) 2.4 ± 4.7 1.5 - 3.4 2.9 ± 5.0 2.4 -3.5 5.3 ± 8.9 4.1- 6.6 <0.0001
s3 (t8-t5) 10.2 ± 8.7 8.4- 11.9 11.5 ± 10.2 10.4 -12.6 21.8 ± 19.1 18.9 - 24.8 <0.0001
t4int (t5-t4) 12.0 ± 5.7 10.9-13.1 11.5 ± 6.5 10.8-12.2 8.7 ± 10.2 7.2-10.1 <0.0001
t5-t2 24.9 ± 5.8 23.8-26.0 24.6 ± 7.8 23.8-25.4 21.9 ± 16.2 19.7-24.2 <0.01
  1. Embryos being cultured for blastocyst transfer cycles (n = 648) were divided into three groups: (A) BL-T, blastocysts transferred, (B) BL-F, blastocysts.
  2. frozen and (C) PQ-D, Poor quality blastocysts/embryos failing to blastulate. Mean timings in BL-T and BL-F blastocysts(Group A, B) shown and compared to Group C. P value <0.05 was considered to be significant.