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Table 3 Embryos kinetics during development to day 5

From: Analysis of embryo morphokinetics, multinucleation and cleavage anomalies using continuous time-lapse monitoring in blastocyst transfer cycles

 

Blasts transferred (BL-T) Mean ± SD

95% CI

Blasts frozen (BL-F) Mean ± SD

95% CI

PQ BL/Non blasts (PQ-D) Mean ± SD

95% CI

p

tPNf

24.8 ± 2.6

24.3- 25.3

25.2 ± 3.0

24.9 - 25.6

26.8 ± 8.3

26.6 - 28.0

0.001

t2

27.2 ± 3.6

26.5 - 27.8

27.7 ± 4.0

27.1-28.2

30.0 ± 8.8

28.8- 31.2

<0.0001

t3

37.6 ± 5.5

36.5-38.7

38.0 ± 5.8

37.4 - 38.6

38 ± 11.8

36.4- 39.6

ns

t4

40.0 ± 5.4

39.0 - 41.1

40.9 ± 6.1

40.3- 41.6

43.4 ± 1 4.3

41.4 - 45.4

0.003

t5

52.0 ± 6.3

50.8 - 53.2

52.4 ± 9.0

51.5 - 53.4

50.2 ± 15.3

48.0 - 52.4

ns

t8

62.1 ± 9.8

60.2- 64.0

63.8 ± 11.7

62.6- 65.1

71.1 ± 21.2

67.8 - 74.3

<0.0001

t9+

73.5 ± 10.3

71.4-75.6

74.7 ± 13.3

73.2-76.3

83.7 ± 24.5

79.7-87.8

<0.0001

tMor

93.9 ± 9.8

91.9 - 95.9

98.2 ± 12.8

96.8 - 99.7

110.7 ± 15.3

106.7 - 114.7

<0.0001

tSB

100.2 ± 7.4

99.0– 101.5

105.5 ± 10.3

104.5 – 106.5

113.1 ± 13.1

110.2 – 116.1

<0.001

tBL

105.2 ± 6.3

103.8 - 106.6

111.1 ± 10.5

109.9 - 112.3

121.4 ± 9.1

116-126.0

<0.0001

tEBL

110.0 ± 5.6

108.6 - 111.4

118.9 ± 12.1

117.3 - 120.4

133.1 ± 9.0

127.1-139.2

<0.0001

cc2 (t3-t2)

10.4 ± 4.5

9.6- 11.3

10.2 ± 4.7

9.7- 10.8

8.6 ± 10.7

7.1 - 10.1

0.02

cc3 (t5-t3)

14.4 ± 5.4

13.4-15.4

14.4 ± 7.3

13.6-15.1

14.0 ± 13.1

12.1-15.8

ns

S1 (t2-tPNf)

2.4 ± 1.7

2.0 – 2.7

2.6 ± 1.9

2.4 -2.8

3.2 ± 3.9

2.6 – 3.7

0.03

s2 (t4-t3)

2.4 ± 4.7

1.5 - 3.4

2.9 ± 5.0

2.4 -3.5

5.3 ± 8.9

4.1- 6.6

<0.0001

s3 (t8-t5)

10.2 ± 8.7

8.4- 11.9

11.5 ± 10.2

10.4 -12.6

21.8 ± 19.1

18.9 - 24.8

<0.0001

t4int (t5-t4)

12.0 ± 5.7

10.9-13.1

11.5 ± 6.5

10.8-12.2

8.7 ± 10.2

7.2-10.1

<0.0001

t5-t2

24.9 ± 5.8

23.8-26.0

24.6 ± 7.8

23.8-25.4

21.9 ± 16.2

19.7-24.2

<0.01

  1. Embryos being cultured for blastocyst transfer cycles (n = 648) were divided into three groups: (A) BL-T, blastocysts transferred, (B) BL-F, blastocysts.
  2. frozen and (C) PQ-D, Poor quality blastocysts/embryos failing to blastulate. Mean timings in BL-T and BL-F blastocysts(Group A, B) shown and compared to Group C. P value <0.05 was considered to be significant.