VEGF-D overexpression suppresses apoptosis of ovarian cancer cells. Tumor tissues were stained with Hoechst 33258. Apoptotic cells are indicated by arrows (A-C). (A) Tumors bearing SKOV3 cells; (B) tumors bearing SKOV3/pcDNA cells; (C) tumors bearing SKOV3/VEGF-D cells. (D) Apoptosis index of tumor cells. P < 0.05 vs. xenografts bearing SKOV3 or SKOV3/pcDNA.