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Table 3 The optimal time interval of kinetic markers predictive of different clinical outcomes by various groups

From: Embryo selection: the role of time-lapse monitoring

  Wong et al. predictive of BC formation [32] Meseguer et al. predictive of implantation [33] Cruz et al. predictive of good morphology blastocyst development [35] Conaghan et al. predictive of blastocyst formation [21] Basile et al. predictive of euploidy [42] Chavez et al. predictive of euploidy [41] Campbell et al. predictive of euploidy [43],[44]
S 1 14.3 ± 6 min      14.4 ± 4.2 min  
CC 2 11.1 ± 2.2 h ≤11.9 h   9.33–11.45 h   11.8 ± 0.71 h  
S 2 1 ± 1.6 h ≤0.76 h ≤ 0.76 h ≤1.73 h   0.96 ± 0.84 h  
t 5   48.8–56.6 h 48.8–56.6 h   47.2–58.2 h   
t 5-2      >20.5 h   
CC 3      11.7–18.2 h   
t BC        <122.9 h (and <96.2 h time to start of blastulation)
  1. S1: duration of first cytokinesis; CC2: t3-2;S2: t4-3;t5: time to 5-cell stage; CC3: t5-3; tBC: time to blastocyst development.