Embryo selection: the role of time-lapse monitoring

Table 3 The optimal time interval of kinetic markers predictive of different clinical outcomes by various groups

	Wong et al. predictive of BC formation [32]	Meseguer et al. predictive of implantation [33]	Cruz et al. predictive of good morphology blastocyst development [35]	Conaghan et al. predictive of blastocyst formation [21]	Basile et al. predictive of euploidy [42]	Chavez et al. predictive of euploidy [41]	Campbell et al. predictive of euploidy [43],[44]
S ₁	14.3 ± 6 min					14.4 ± 4.2 min
CC ₂	11.1 ± 2.2 h	≤11.9 h		9.33–11.45 h		11.8 ± 0.71 h
S ₂	1 ± 1.6 h	≤0.76 h	≤ 0.76 h	≤1.73 h		0.96 ± 0.84 h
t ₅		48.8–56.6 h	48.8–56.6 h		47.2–58.2 h
t _5-2					>20.5 h
CC ₃					11.7–18.2 h
t _BC							<122.9 h (and <96.2 h time to start of blastulation)

S₁: duration of first cytokinesis; CC₂: t_3-2;S₂: t_4-3;t₅: time to 5-cell stage; CC₃: t5-3; t_BC: time to blastocyst development.

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