In high responding patients undergoing an initial IVF cycle, elevated estradiol on the day of hCG has no effect on live birth rate

Table 7 Response variables for the entire population and subgroup having good/fair quality embryos transferred on day 5

Variables	Entire population		Good/fair embryos only
Variables	Non-LB	LB	Non-LB	LB
Number	75 (36.9%)	128 (63.1%)*	67 (34.7%)	126 (65.3%)**
Patient age	30.9 ± 4.1	30.9 ± 3.7	30.6 ± 4.1	30.9 ± 3.7
FSH dose (IU)	2798 ± 1250^a	2204 ± 1124^a	2702 ± 1189^c	2203 ± 1130^c
Estradiol on day of hCG pg/ml	3226 ± 1132	3390 ± 1092	3375 ± 1088	3391 ± 1090
BMI	26.0 ± 6.7	25.5 ± 5.9	25.9 ± 6.7	25.4 ± 5.9
Number retrieved oocytes	21.6 ± 8.3	23.9 ± 8.3	22.4 ± 7.9	23.8 ± 8.3
MII eggs	16.9 ± 6.9^b	19.4 ± 7.0^b	17.7 ± 6.6	19.4 ± 7.0
Number of 2PN	12.2 ± 5.3	13.5 ± 4.9	12.7 ± 5.1	13.5 ± 4.9
Number of embryos transferred	1.87 ± 0.41	1.91 ± 0.36	1.85 ± 0.40	1.90 ± 0.37
AEQS	1.66 ± 0.60^d	1.51 ± 0.46^d	1.51 ± 0.42	1.49 ± 0.43

All values are Mean ± 1SD.
Differences within row comparing the same response variable by pregnancy status (NLB or LB) for the entire population or patients having only good or fair quality embryos transferred having the same superscript are different; ^ap <0.001; ^bp < 0.010, ^cp < 0.007, ^dp <0.040.
*Chi Square comparison for difference between Day 3 and Day 5 in the total population for Live Birth was p < 0.02.
**Chi Square comparison for difference between Day 3 and Day 5 in populations with only good or fair quality embryos used for transfer was NS.

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