Fine morphological assessment of quality of human mature oocytes after slow freezing or vitrification with a closed device: a comparative analysis

Table 1 Morphometric evaluation of the presence and extent of vacuolization in human MII oocytes subjected to slow freezing and vitrification with a closed device

	Fresh controls (CO)	Cryopreserved
	Fresh controls (CO)	Slow frozen/thawed (SFO)	Vitrified/warmed (VO)
N° of vacuoles/100 μm² (vacuole diameter ≥1 μm)	0.40 ± 0.12^a	2.09 ± 0.85^b	0.85 ± 0.37^c

Values are expressed as mean ± SD. Statistical analysis is calculated between columns. Differences in values were considered significant if P <0.05.
^a,bP <0.0001; ^a,cP = 0.0005; ^b,cP <0.0001.

ISSN: 1477-7827