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Table 4 Fertilisation and embryo development in the ANA + group and the ANA- group

From: A retrospective study on IVF/ICSI outcome in patients with anti-nuclear antibodies: the effects of prednisone plus low-dose aspirin adjuvant treatment

Variables ANA + group ANA- group P
OPU cycles (IVF + ICSI) 66 (28 + 38) 233 (106 + 127) -
ET cycles 52 184 ns
Proportion of ICSI program (%) 57.6 (38/66) 54.5 (127/233) ns
Semen volume (ml, ICSI cycles) 3.46+/-0.74 3.96+/-0.86 ns
Sperm concentration (×106/ml, ICSI cycles) 16.86+/-13.34 15.45+/-11.23 ns
Sperm progressive motility (%, ICSI cycles) 11.97+/-9.74 10.96+/-8.44 ns
Semen volume (ml, IVF cycles) 3.67+/-0.87 3.86+/-0.84 ns
Sperm concentration (×106/ml, IVF cycles) 65.33+/-44.33 68.84+/-46.00 ns
Sperm progressive motility (%, IVF cycles) 40.28+/-16.78 35.23+/-15.84 ns
Retrieved oocytes 9.73 +/- 5.03 10.38 +/- 4.15 ns
MII oocytes rate (%, ICSI cycle) 78.1 (285/365) 82.6 (1112/1346) 0.047
Normal fertilisation rate (%, ICSI cycle) 70.5 (201/285) 83.1 (924/1112) <0.001
Abnormal fertilisation rate (%, ICSI cycle) 4.91 (14/285) 0.36 (4/1112) <0.001
Normal fertilisation rate (%, IVF cycle) 66.1 (183/277) 76.0 (815/1073) <0.001
Abnormal fertilisation rate (%, IVF cycle) 4.33 (12/277) 2.33 (23/1073) 0.041
Cleavage rate (%) 97.7 (375/384) 98.5 (1713/1739) ns
Perfect embryo rate (%) 63.7 (239/375) 66.5 (1139/1713) ns
Available embryo rate (%) 78.7 (295/375) 82.9 (1420/1713) ns
Transferred embryos/cycle 2.12 ± 0.55 2.11 ± 0.38 ns
  1. P<0.05 was considered to be statistically significant.
  2. Note: Sperm with progressive motility, including those that move fast in a straight line (grade a) and that move forward but tend to travel in a curved or bent motion (grade b). MII oocytes rate = M II oocytes/total oocytes in the ICSI cycle; normal fertilisation rate = 2PNs /total M II oocytes in the ICSI cycle or 2PNs/total oocytes in the IVF cycle; abnormal fertilisation rate = 1PNs + multi-PNs/total M II oocytes in the ICSI cycle or 1PNs + multi-PNs/total oocytes in the IVF cycle.