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Table 4 Fertilisation and embryo development in the ANA + group and the ANA- group

From: A retrospective study on IVF/ICSI outcome in patients with anti-nuclear antibodies: the effects of prednisone plus low-dose aspirin adjuvant treatment

Variables

ANA + group

ANA- group

P

OPU cycles (IVF + ICSI)

66 (28 + 38)

233 (106 + 127)

-

ET cycles

52

184

ns

Proportion of ICSI program (%)

57.6 (38/66)

54.5 (127/233)

ns

Semen volume (ml, ICSI cycles)

3.46+/-0.74

3.96+/-0.86

ns

Sperm concentration (×106/ml, ICSI cycles)

16.86+/-13.34

15.45+/-11.23

ns

Sperm progressive motility (%, ICSI cycles)

11.97+/-9.74

10.96+/-8.44

ns

Semen volume (ml, IVF cycles)

3.67+/-0.87

3.86+/-0.84

ns

Sperm concentration (×106/ml, IVF cycles)

65.33+/-44.33

68.84+/-46.00

ns

Sperm progressive motility (%, IVF cycles)

40.28+/-16.78

35.23+/-15.84

ns

Retrieved oocytes

9.73 +/- 5.03

10.38 +/- 4.15

ns

MII oocytes rate (%, ICSI cycle)

78.1 (285/365)

82.6 (1112/1346)

0.047

Normal fertilisation rate (%, ICSI cycle)

70.5 (201/285)

83.1 (924/1112)

<0.001

Abnormal fertilisation rate (%, ICSI cycle)

4.91 (14/285)

0.36 (4/1112)

<0.001

Normal fertilisation rate (%, IVF cycle)

66.1 (183/277)

76.0 (815/1073)

<0.001

Abnormal fertilisation rate (%, IVF cycle)

4.33 (12/277)

2.33 (23/1073)

0.041

Cleavage rate (%)

97.7 (375/384)

98.5 (1713/1739)

ns

Perfect embryo rate (%)

63.7 (239/375)

66.5 (1139/1713)

ns

Available embryo rate (%)

78.7 (295/375)

82.9 (1420/1713)

ns

Transferred embryos/cycle

2.12 ± 0.55

2.11 ± 0.38

ns

  1. P<0.05 was considered to be statistically significant.
  2. Note: Sperm with progressive motility, including those that move fast in a straight line (grade a) and that move forward but tend to travel in a curved or bent motion (grade b). MII oocytes rate = M II oocytes/total oocytes in the ICSI cycle; normal fertilisation rate = 2PNs /total M II oocytes in the ICSI cycle or 2PNs/total oocytes in the IVF cycle; abnormal fertilisation rate = 1PNs + multi-PNs/total M II oocytes in the ICSI cycle or 1PNs + multi-PNs/total oocytes in the IVF cycle.