MicroRNAs expression profiling of eutopic proliferative endometrium in women with ovarian endometriosis

Table 2 The 15 top-regulated miRNAs, showing high probability of differential regulation between the eutopic endometrium of patients with and without ovarian endometriosis

Nr	miRNA	Endometriosis				Control
Nr	miRNA	Mean	std. deviation	Coefficient of variation	Max/min R	Mean	std. deviation	Coefficient of variation	Max/min R	Mean difference	Median difference	Mean fold- change	Median fold- change
1	hsa-miR-24	1.29	0.04	3.12	1.089	1.16	0.08	6.87	1.21	1.11	1.17	1.11	1.17
2	hsa-miR-885-5p	4.18	3.92	93.75	12.25	2.06	1.23	59.96	9.22	2.02	1.21	2.02	1.21
3	hsa-miR-26b	1.38	0.43	31.37	2.69	3.04	3.60	118.48	12.84	0.45	0.92	−2.19	−1.08
4	hsa-let-7b	1.002	0.32	32.48	3.11	1.37	0.39	28.64	2.352	0.730	0.870	−1.369	−1.149
5	hsa-miR-185	0.98	0.42	42.89	5.69	1.52	0.74	48.87	4.3	0.69	0.81	−1.54	−1.23
6	hsa-miR-142-3p	1.81	1.07	58.93	8.57	3.03	1.61	53.12	5.43	0.6	0.56	−1.66	−1.76
7	hsa-miR-29b	0.96	0.64	66.84	9.34	1.73	0.96	55.89	5.78	0.55	0.59	−1.79	−1.68
8	hsa-miR-483-5p	0.75	0.58	76.80	22.55	1.34	0.76	56.75	8.29	0.56	0.43	−1.77	−2.31
9	hsa-miR-144*	0.14	0.085	57.82	8.9	0.49	0.29	60.68	6.65	0.3	0.34	−3.31	−2.89
10	hsa-miR-145*	1.04	0.8	77.46	12.37	2.39	1.8	75.38	8.9	0.43	0.34	−2.3	−2.94
11	hsa-miR-629*	1.53	1.352	87.88	15.1	1.9	1.31	69.05	10	0.80	0.48	−1.24	−2.06
12	hsa-miR-222*	0.71	0.44	61.54	16.70	1.47	1.23	83.64	13.48	0.48	0.69	−2.056	−1.44
13	hsa-miR-497	0.61	0.37	60.51	16.68	1.29	1.26	97.74	16.98	0.47	0.58	−2.12	−1.7
14	hsa-miR-675	1.09	0.77	70.73	17.08	2.66	2.26	84.87	12.03	0.41	0.54	−2.42	−1.84
15	hsa-miR-106b*	0.572	0.571	99.96	72.356	1.44	1.9	131.84	39.01	0.39	0.48	−2.53	−2.04

R represents the ratio between the max and min values within one replicate group (see Material and Methods for a detailed description).

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