Figure 2

Testosterone levels in patients with and without presumed immune activation. A demonstrates TT and B FT levels; both were, overall, among women with autoimmunity significantly elevated (P = 0.004 and P < 0.001, respectively) but in women with POA/OPOI and DOR significantly diminished (both P < 0.001) in comparison to controls. Women without evidence of immune system activation, in contrast, overall, demonstrated lower androgen levels (as noted above) and did not differ in either TT or FT between controls and POA/OPOI and physiologic DOR patients.