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Figure 6 | Reproductive Biology and Endocrinology

Figure 6

From: Fertility in a high-altitude environment is compromised by luteal dysfunction: the relative roles of hypoxia and oxidative stress

Figure 6

Representative images of immunohistochemical expression of hypoxia inducible factor 1α and vascular endothelial growth factor in corpora lutea from cycling sheep at a high altitude. Images A and B show sections of luteal tissue with high and low HIF-1α expression, respectively. The arrows show examples of luteal cells expressing the protein. Image C corresponds to a control section prepared in the absence of HIF-1α antibody. Images D and E show sections of luteal tissue with high and low VEGF expression, respectively. The arrows show blood vessels where VEGF staining was denser. Image F corresponds to a control tissue section prepared in the absence of VEGF antibody. Magnification 400×.

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