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Table 2 Controlled ovarian stimulation, embryological data and IVF outcome

From: IVF outcome is optimized when embryos are replaced between 5 and 15 mm from the fundal endometrial surface: a prospective analysis on 1184 IVF cycles

 

All

EFD (mm)

p

  

<5

5-9.9

10-15

>15

 
 

(n = 1184)

(n = 59)

(n = 548)

(n = 429)

(n = 148)

 

Gonadotropin total dose (IU)

2255 ± 1065

2178 ± 863

2205 ± 1099

2283 ± 1070

2390 ± 981

ns

n. of retrieved oocytes

8.7 ± 5.2

9.7 ± 5.3

8.5 ± 5.2

8.6 ± 5.1

8.9 ± 5.3

ns

n. of fertilized oocytes

5 ± 2.6

5.7 ± 2.7

5 ± 2.6

5 ± 2.6

5.1 ± 2.5

ns

endometrial thickness (mm)

10.5 ± 2.6

9.7 ± 2.2

10.0 ± 2.5

11.0 ± 2.5

11.7 ± 3.0

ns

n. of transferred embryos/ET

1.9 ± 0.5

1.9 ± 0.5

1.9 ± 0.5

1.9 ± 0.6

1.9 ± 0.6

ns

Mean embryo score

8.1 ± 1.8

7.9 ± 1.8

8.2 ± 0.7

8.0 ± 0.8

8.1 ± 0.8

ns

n. of top scored embryos/ET

0.5 ± 0.8

0.9 ± 1.4

0.5 ± 0.8

0.5 ± 0.8

0.4 ± 0.7

ns

n. of pregnancies

476

24

227

186

39

 

CPR/ET (%)

40.2

40.7

41.4

43.4

26.4*

0.003

Implantation rate (IR)

19.9

19.7

20.9

20.9

12.9*

0.02

Abortion rate (AR)

21.4

42.1

17.9

22.0

26.5

ns

Ongoing pregnancies at 10 W

374

14

187

145

29

 

Ongoing PR/ET

31.6

23.7

34.1

33.8

19.6

ns

  1. Patients were subgrouped according to the site at which embryos were transferred (EFD = distance between the hyperecogenic spot and the basal layer of the endometrial fundus).
  2. *significance level of this subgroup vs. all others.