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Table 3 The embryos quality and outcome of IVF-ET

From: Endometriosis fertility index score maybe more accurate for predicting the outcomes of in vitrofertilisation than r-AFS classification in women with endometriosis

Characteristic

 

EFI

r-AFS

Total

≤5 score

≥6 score

z (χ 2 )

P c

I-II stage

III-IV stage

z (χ2)

P d

No. of cycles

199

84

115

  

61

138

  

No. of oocytes retrieveda

8.0(4.0–12.0)

6.0(3.0–10.8)

9.0(5.0–14.0)

−3.071

0.002

9.0(5.0–15.0)

7.0(3.0–11.3)

−2.454

0.014

No. of fertilization

5.0(3.0–9.0)

4.0(2.0–8.0)

6.0(4.0–10.0)

−3.292

0.001

6.0(4.0–10.0)

5.0(2.8–8.0)

−2.493

0.013

No. of fertilization 2PNa

4.0(2.0-7.0)

3.5(1.0-7.0)

5.0(3.0–8.0)

−2.735

0.006

5.0(3.0–9.0)

4.0(2.0-7.0)

−1.851

0.064

Rate of 2PN fertilizationb

1082/1834(59.0%)

414/676(61.2)

668/1158(57.7)

2.232

0.135

379/671(56.5)

703/1163(60.4)

2.764

0.096

Rate of polypronucleus zygote(%)b

154/1834(8.4%)

51/676(7.5)

103/1158(8.9)

1.012

0.314

70/671(10.4)

84/1163(7.2)

5.698

0.017

No. of cleavage from 2PN

4.0(2.0–7.0)

3.0(1.0-6.0)

5.0(3.0–7.0)

−2.980

0.003

5.0(3.0–9.0)

4.0(2.0–6.0)

−2.082

0.037

Cleavage rate from 2PN zygoteb

1045/1236(84.5)

391/465(84.1)

654/771 (84.8)

0.121

0.728

372/449(82.9)

673/787(85.5)

0.696

0.404

Availability of embryos(%)b

924/1306(70.8)

347/496(70.0)

577/810(71.2)

0.242

0.623

310/475(65.3)

614/831(73.9)

10.862

0.001

Top quality embryos(%)b

139/1045(13.3)

53/391(13.6)

86/654(13.1)

0.035

0.852

52/372(13.9)

87/673(12.9)

0.230

0.632

No. Of embryos transferred

2.0(2.0–2.0)

2.0(1.0–2.75)

2.0(2.0-2.0)

−1.920

0.055

2.0(2.0–3.0)

2.0(2.0–2.0)

−2.349

0.019

Implantation rate(%)b

120/386(31.1)

37/148(25.0)

83/238(34.9)

4.153

0.042

43/131(32.8)

77/255(30.2)

0.279

0.597

Clinical pregnancy rate(%)b

85/199(42.7)

24/84(28.6)

61/115(53.0)

11.881

0.001

31/61(50.8)

54/138(39.1)

2.362

0.124

Accumulation rate of pregnancyb

107/199(53.8)

33/84(39.2)

74/115(64.3)

12.266

0.000

37/61(60.7)

70/138(50.7)

1.678

0.195

  1. Note: Rate of 2PN fertilisation = number of 2PN zygotes/number of oocytes retrieved; rate of polypronucleus zygotes = number of polypronucleus zygotes/number of oocytes retrieved; rate of cleavage from 2PN = number of cleavages from 2PN/number of zygotes; embryo availability rate = (number of frozen embryos + number of ET embryos)/number of cleavage-stage embryos; top-quality embryos = number of top-quality embryos/number of cleavage-stage embryos from 2PN; implantation rate = number of gestational sacs/number of ET embryos; clinical pregnancy rate = number of pregnancy cycles/number of embryo transfer cycles; accumulation rate of pregnancy = number of pregnancy cycles for fresh transferred embryos or freeze-thawed transferred embryos in a single cycle of ovulation stimulation/number of cycles for ovulation stimulation.
  2. Definition of top-quality embryo: seven to eight blastomeres of equal size and less than 10% fragmentation can be seen on day 3 ( Alpha Scientists in Reproductive Medicine and ESHRE Special Interest Group of Embryology, 2011) [19].
  3. aThe non-normally distributed data are presented as median (25th-75th percentile). The non-parametric Mann–Whitney test was performed to calculate the Z-score.
  4. bThe chi-squared test was performed to compare rates between groups.
  5. cComparison between the EFI score ≤5 and ≥6 groups. (score ≤5 vs score ≥6).
  6. dComparison between the r-AFS stage I-II and stage III-IV groups (stage I-II vs stage III-IV).
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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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