Transcripts levels of the target genes ( RUNX2 , PSAT1 , ADAMTS9 , CXCL1 , CXCL2 , CXCL3 , ITGB5 , GPX3 and PTX3 ) according to oocyte nuclear maturity in PCOS patients. mRNA expression of candidate genes (RUNX2, PSAT1, ADAMTS9, CXCL1, CXCL2, CXCL3, ITGB5, GPX3 and PTX3) in cumulus cells of PCOS patients, organized according to oocyte nuclear maturity stage (MI/GV stage versus MII stage). The signal intensity for each gene is shown on the y-axis in arbitrary units determined by qRT-PCR analysis with GAPDH as an endogeneous reference. * indicates a significant difference in gene expression between CC categories (** p < 0.01, * p < 0.05). The results are presented as the means ± SEM. CCMI/GV: cumulus cells from oocyte at the MI stage or GV stage; CCMII: cumulus cells from oocyte at the MII stage.