Castration-induced testosterone deficiency increases fasting glucose associated with hepatic and extra-hepatic insulin resistance in adult male rats

Table 1 The body weight, blood glucose, testosterone and estrogen levels of the three groups of rats at the end of the study (+/−s)

	C	TD	TD + TP	P value
	(n = 10)	(n = 10)	(n = 10)	P value
Body weight (g)	629+/−66.93	502.86+/−66.88*	546+/−44.63*	0.0188
RBG (mmol/L)	4.46+/−1.08	5.36+/−0.67	4.98+/−0.438	0.1696
FBG (mmol/L)	4.56+/−1.173	5.514+/−0.705*^#	3.34+/−1.171	0.0082
T (ng/mL)	2.96+/−0.55	1.45+/−0.26*^#	2.07+/−0.35*	0.0053
E2 (pg/mL)	8.2+/−2.08	6.4+/−2.05	8.4+/−1.52	0.065

C, control group, rats underwent sham surgery; TD, testosterone deficiency group, rats underwent bilateral orchidectomy surgery; TD + TP, castrated rats given testosterone; RBG, random blood glucose; FBG, fasting blood glucose; T, testosterone; E2, estrogen; Data are presented as the means +/− SD.
*, compared with the control group (C).
#, compared with castrated rats replaced with testosterone propionate (TD + TP).

ISSN: 1477-7827